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A Vaccine can be defined as a biological preparation that provides active acquired immunity to a particular disease. A vaccine typically consists of a disease-causative microorganism which is often prepared from killed or inactivated forms of the microbe, its toxins or one of its surface proteins. This agent stimulates the body's immune system to recognize it as threat, destroy it, and maintain a record of it, and any such successive similar infection can be more easily recognized by the immune system and destroyed.

Vaccines have been our best weapon against the world’s deadliest infectious diseases, including smallpox, polio, measles, and yellow fever. An effective virulent HIV vaccine would enable the body to fight with HIV virus and suppressing the symptoms of infection. Vaccines are the most powerful public health tools available and an AIDS vaccine would play a powerful role in ensuring the end to the AIDS epidemic. A HIV vaccine does not yet exist, but efforts to develop a vaccine against HIV, the virus that causes AIDS, have been underway for many years.

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